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Oregon vs Oklahoma State: Ducks Favored

Oregon Ducks visit Oklahoma State Cowboys on Saturday, Sept. 12, 2026 at 12 p.m. ET from Boone Pickens Stadium. Ducks are favored by 22.5 points after Moore's impressive 378-yard passing performance in their opener.

Oregon Ducks (1-0) face off against Oklahoma State Cowboys (0-1) on Saturday at 12 p.m. ET. The Ducks are coming off a 34-27 win over Boise State where quarterback Dante Moore threw for 378 yards. Oklahoma State lost to Tulsa 24-10 with quarterback Drew Mestemaker completing 29 of 49 passes for 241 yards with a touchdown and two interceptions. biznow.biz

The Ducks are 22.5-point favorites with a total of 57.5 points. Oregon's quarterback Dante Moore and receiver Jeremiah McClellan will be key players to watch, as will Oklahoma State's quarterback Drew Mestemaker who needs a cleaner performance after his Week 1 struggles.